Advanced night serum with retinol, peptide and ageLOC technology
ageLOC Tru Face Peptide Retinol Complex is an advanced serum for evening care of the face and neck, developed with visible signs of aging, uneven skin tone, pigmentation, fine lines and deeper wrinkles, skin texture and the appearance of pores in mind.
The formula combines ageLOC technology, Retinol Complex, an AI-identified peptide and the soothing Jojoba + 4TB Blend. The product was developed to provide effective yet comfortable care and to be suitable for regular evening use.
Regular use helps to:
- reduce the appearance of fine lines and deeper wrinkles;
- support smoother, more resilient-looking skin;
- reduce the appearance of pores;
- improve the look of skin texture;
- support a more even-looking skin tone;
- reduce the visibility of dark spots and uneven pigmentation;
- support elasticity and a firmer-looking complexion;
- promote a brighter, fresher and more radiant appearance.
Size: 30 ml. The product is also available in a system with a replaceable 30 ml refill.
What makes ageLOC Tru Face Peptide Retinol Complex special?
This serum is not based on classic retinol alone.
Its formula combines several technologies with complementary functions:
- Retinol Complex – two types of retinoids;
- Advanced Peptide Technology – an AI-identified peptide;
- ageLOC Blend – technology focused on visible signs of aging;
- Jojoba + 4TB Blend – support for comfort, soothing and hydration.
This allows the product to combine care for texture, skin tone, elasticity, wrinkles, pores and pigmentation in one evening step.
Retinol Complex – two types of retinoids
The formula contains stabilized pure retinol and Hydroxypinacolone Retinoate (HPR), an ester of retinoic acid.
This combination helps support the skin’s natural renewal processes and improve the appearance of:
- fine lines and deeper wrinkles;
- uneven skin tone;
- texture;
- elasticity;
- dark spots and uneven pigmentation.
Retinoids are cosmetic ingredients associated with skin-surface renewal processes, so it is important to introduce them appropriately into a routine and use suitable sun protection during the day.
Advanced Peptide Technology – a peptide identified with AI
One of the most distinctive elements of the formula is Oligopeptide-1, described in Nu Skin materials as a peptide identified with the help of artificial intelligence, clinically tested and identical to a naturally occurring peptide focused on visible signs of aging.
The peptide technology was developed to complement the Retinol Complex and support:
- more youthful-looking skin;
- resilience;
- a smoother appearance;
- reduced visibility of fine lines and deeper wrinkles.
In practice, this means the care profile is not based on a single active ingredient.
ageLOC Blend – care for visible signs of aging
The formula also contains ageLOC Blend, Nu Skin’s characteristic technology used in products focused on visible signs of aging.
In this serum, it supports a comprehensive approach to the appearance of the skin and helps maintain a more youthful and energized look.
This does not mean stopping the biological aging process. It is cosmetic skincare focused on the visible appearance of the skin.
Jojoba + 4TB Blend – comfort when using retinoids
Products containing retinol can be more demanding on the skin, so the formula also includes Jojoba + 4TB Blend.
This combination helps to:
- hydrate;
- support skin comfort;
- relieve sensations associated with dryness;
- support the skin’s natural moisture barrier.
This means the more intensive active profile is balanced by ingredients designed to support skin comfort.
Less visible fine lines and deeper wrinkles
One of the main purposes of Peptide Retinol Complex is to care for skin with visible lines and wrinkles.
The combination of retinoids and peptide technology helps support:
- a smoother-looking complexion;
- reduced appearance of fine lines;
- reduced appearance of deeper wrinkles;
- a more resilient and fuller-looking complexion.
Reducing the appearance of fine lines and deeper wrinkles is among the key cosmetic benefits of the product.
Support for a more even-looking skin tone
Peptide Retinol Complex may be especially interesting for people who notice:
- uneven skin tone;
- dark spots;
- visibly uneven pigmentation;
- loss of radiance.
Retinol Complex helps reduce the appearance of dark spots and uneven pigmentation while supporting improved texture and overall skin appearance.
Less visible pores and smoother texture
The serum also helps reduce the appearance of pores and supports smoother, more refined-looking skin texture.
Regular care can help the skin appear:
- smoother;
- more even;
- less rough;
- softer;
- visually more refined.
Reduced pore visibility and improved skin texture are among the main benefits of the product.
Resilience, elasticity and a more youthful appearance
Peptide Retinol Complex also supports characteristics associated with more resilient and youthful-looking skin.
The care profile focuses on supporting:
- elasticity;
- a firmer appearance;
- resilience;
- smoothness;
- an overall more youthful look.
This is a cosmetic effect related to the appearance and feel of the skin, not a change in its biological age.
Visible results after just 7 days
In the product evaluation, visible improvements in some assessed aspects of skin appearance were observed after just 7 days of using Peptide Retinol Complex.
An internal 8-week in vivo evaluation included 31 healthy women and men aged 35–70, who used the product once daily in the evening.
The evaluation included elasticity, firmness and skin-barrier parameters, while participants also completed self-assessments.
What did participants notice after 1 week?
After 1 week of use:
- 87% of participants agreed that their skin looked and felt more energized and healthier;
- 83% said their skin looked and felt more revitalized;
- 80% noticed a brighter-looking complexion;
- 80% said their pores appeared less visible;
- 80% agreed that their skin felt comfortable and balanced.
These were participant self-assessments under the specific conditions of the study. Individual results may vary.
What did participants notice after 8 weeks?
After 8 weeks:
- 100% of participants agreed that wrinkles appeared less pronounced;
- 100% said the skin looked more resilient and fuller;
- 100% agreed that imperfections appeared less visible;
- 97% said pores appeared less visible;
- 97% said the product supported a more youthful appearance;
- 97% rated their skin as brighter and more radiant;
- 93% noticed a lighter and brighter-looking complexion.
These results reflect participant self-assessment in a specific evaluation and do not guarantee identical results for every person.
What did the instrumental measurements show?
In the same evaluation, measurable changes were also observed after a single application:
- 64% improvement in elasticity;
- 38% improvement in skin-barrier parameters;
- 20% improvement in firmness.
The results relate to the specific evaluation methodology and instrumental measurements used. Individual results may vary.
Peptide Retinol Complex + Essence Ultra – a clinically evaluated combination
Nu Skin also conducted a 12-week in vivo evaluation involving 10 healthy women and men, in which Peptide Retinol Complex was used once daily in the evening and ageLOC Tru Face Essence Ultra twice daily.
After 12 weeks, expert assessment observed, among other findings:
- improved skin texture in 100% of participants;
- reduced appearance of fine lines and deeper wrinkles in 90%;
- reduced appearance of pores in 90%;
- improved appearance of contours, firmness and lift in 90%;
- reduced appearance of crow’s feet in 70%.
These results relate to the combined Peptide Retinol Complex + Essence Ultra protocol, not to Peptide Retinol Complex alone.
How to use ageLOC Tru Face Peptide Retinol Complex
Step 1 – cleanse the skin
Cleanse the face and neck thoroughly in the evening.
Step 2 – apply toner
If you use ageLOC Tru Face Refining Toner, apply it after cleansing and before Peptide Retinol Complex.
Step 3 – apply Peptide Retinol Complex
Apply the serum to the face and neck once daily in the evening.
For a more comprehensive routine, the product can also be applied to the décolletage and backs of the hands, areas where visible signs of aging may also appear.
Step 4 – continue with another serum if it is part of your routine
If you use Essence Ultra or another suitable product, apply it according to the order of your routine.
Step 5 – finish with moisturizer
Complete the routine with a suitable moisturizer.
How often should Peptide Retinol Complex be used?
Once daily, in the evening.
Simple order:
cleanse → Refining Toner → Peptide Retinol Complex → moisturizer
For a more complete routine:
cleanse → Refining Toner → Peptide Retinol Complex → Essence Ultra → moisturizer
Why is it best to use the serum in the evening?
Retinol can increase the skin’s sensitivity to sunlight, especially during the first weeks of use.
For this reason, Peptide Retinol Complex is intended for an evening routine. In the morning, use appropriate broad-spectrum sun protection.
SPF is an important part of a routine with retinol
When using a retinol product, sun protection should be considered a regular part of the morning routine.
A simple approach:
evening: cleanse → toner → Peptide Retinol Complex → moisturizer
morning: cleanse → toner → serum → moisturizer → SPF
Especially when beginning to use retinol, it is sensible to limit excessive sun exposure.
Peptide Retinol Complex and Refining Toner – preparation before retinol
ageLOC Tru Face Refining Toner fits naturally into the routine before Peptide Retinol Complex.
Refining Toner:
- prepares the skin;
- supports hydration;
- refreshes;
- supports the natural moisture barrier.
Peptide Retinol Complex then provides a more concentrated step focused on visible signs of aging.
Order:
cleanse → Refining Toner → Peptide Retinol Complex → moisturizer
Discover ageLOC Tru Face Refining Toner
Peptide Retinol Complex and Essence Ultra – when firmness is also a priority
This is a particularly natural combination because Peptide Retinol Complex + Essence Ultra was evaluated together in a clinical study.
Peptide Retinol Complex focuses, among other things, on:
- wrinkles;
- texture;
- pores;
- dark spots and uneven pigmentation;
- skin tone.
Essence Ultra complements the routine with greater focus on:
- firmness;
- elasticity;
- contours;
- a more lifted-looking appearance.
Evening order:
cleanse → Refining Toner → Peptide Retinol Complex → Essence Ultra → moisturizer
Discover ageLOC Tru Face Essence Ultra
Peptide Retinol Complex and Uplifting Rich Cream – a richer evening routine
If you want to use a richer, more nourishing cream after your retinol serum, ageLOC Tru Face Uplifting Rich Cream can be a suitable next step.
Order:
cleanse → Refining Toner → Peptide Retinol Complex → Uplifting Rich Cream
This routine may be especially interesting if you are looking for:
- greater comfort;
- more intensive hydration;
- care for a firmer-looking complexion;
- a more complete evening routine.
Discover ageLOC Tru Face Uplifting Rich Cream
Peptide Retinol Complex and Transforming Gel Cream – a lighter finish
If you prefer a lighter cream texture, you can apply ageLOC Tru Face Transforming Gel Cream after Peptide Retinol Complex.
Order:
cleanse → Refining Toner → Peptide Retinol Complex → Transforming Gel Cream
Discover ageLOC Tru Face Transforming Gel Cream
Peptide Retinol Complex and Radiant Day – separate evening and morning care
Use Peptide Retinol Complex in the evening, while ageLOC Tru Face Radiant Day can be part of your morning routine.
Example:
evening:
cleanse → Refining Toner → Peptide Retinol Complex → moisturizer
morning:
cleanse → Refining Toner → serum → Radiant Day
Radiant Day contains SPF 22, but the level of sun protection required should be adapted to individual needs and actual sun exposure.
Discover ageLOC Tru Face Radiant Day
Is the product suitable for sensitive skin?
The formula was developed with gentleness and comfort in mind and may be suitable for some people with sensitive skin.
However, every skin type may respond differently to a new product, particularly one containing retinoids.
For sensitive skin, it is sensible to:
- perform a patch test on a small area first;
- observe the skin’s response;
- not exceed one application per day;
- discontinue use if persistent irritation develops.
Can Peptide Retinol Complex be used every day?
Yes. The product is designed for daily use once each evening.
However, tolerance to retinoids varies from person to person. People who have not used retinol before should pay particular attention to their skin’s response and should not ignore signs of irritation.
Can the serum replace moisturizer?
No.
Peptide Retinol Complex is a concentrated serum.
After applying it, finish the routine with a suitable moisturizer to provide additional hydration and comfort.
Can Peptide Retinol Complex be used in the morning?
The product is primarily intended for an evening routine, once daily.
In the morning, focus on hydration and suitable sun protection.
Is SPF necessary when using retinol?
Yes. Retinol can increase the skin’s sensitivity to sunlight, especially during the first weeks of use.
Use appropriate sun protection during the day and limit excessive UV exposure.

